{"product_id":"ikaros-3-polyclonal-antibody-ra26218","title":"Ikaros 3 Polyclonal Antibody - RA26218","description":"\u003cp\u003eIkaros 3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA26218-50, RA26218-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: IKAROS family zinc finger 3 (IKZF3) Homo sapiens This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros\/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: IKZF3; ZNFN1A3; Zinc finger protein Aiolos; Ikaros family zinc finger protein 3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 22806\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 62\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9UKT9\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121345323187,"sku":"RA26218-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121345355955,"sku":"RA26218-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_38d90fd4-11eb-4d48-94b4-e8bb31ef29d6.png?v=1773346661","url":"https:\/\/afsbio.com\/products\/ikaros-3-polyclonal-antibody-ra26218","provider":"AFSBio Inc.","version":"1.0","type":"link"}