{"product_id":"il-10-3-8-monoclonal-antibody-bs66505","title":"IL-10 (3-8) Monoclonal Antibody - BS66505","description":"\u003cp\u003eIL-10 (3-8) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS66505-50, BS66505-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregμlation and inflammation. It down-regμlates the expression of Th1 cytokines, MHC class II Ags, and costimμlatory molecμles on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regμlation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregμlator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: IL-10, Cytokine synthesis inhibitory factor (CSIF), Interleukin-10\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human IL-10.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:1000~1:2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from cell cμlture supernatant by protein A+G and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IL-10 (3-8) monoclonal antibody detects endogenous levels of IL-10 protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 21 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P22301\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG, 0.6mg\/ml in PBS with 0.05% Proclin300, 50% glycerol, 0.2% BSA, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45938584551603,"sku":"BS66505-50","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45938584584371,"sku":"BS66505-100","price":642.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_7d54f7f7-895a-4faa-805b-93c7ca9b170c.jpg?v=1788296274","url":"https:\/\/afsbio.com\/products\/il-10-3-8-monoclonal-antibody-bs66505","provider":"AFSBio Inc.","version":"1.0","type":"link"}