{"product_id":"il-15-polyclonal-antibody-bt-ap10287","title":"IL-15 Polyclonal Antibody - BT-AP10287","description":"\u003cp\u003eIL-15 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10287-20, BT-AP10287-50, BT-AP10287-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each otherandapos;s activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1\/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Immunology; Metabolism; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: IL15\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Interleukin-15\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P40933; Mouse: P48346\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Interleukin-15;IL-15; Interleukin-15; IL-15\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3600; Mouse: 16168\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239176822963,"sku":"BT-AP10287-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239176855731,"sku":"BT-AP10287-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239176888499,"sku":"BT-AP10287-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_56b4e5b2-405f-4285-9d0f-d22ebd62268e.png?v=1769390186","url":"https:\/\/afsbio.com\/products\/il-15-polyclonal-antibody-bt-ap10287","provider":"AFSBio Inc.","version":"1.0","type":"link"}