{"product_id":"il-4r-cd124phospho-y497-polyclonal-antibody-ap0132","title":"IL-4R\/CD124(Phospho-Y497) Polyclonal Antibody-AP0132","description":"\u003cp\u003eIL-4R\/CD124(Phospho-Y497) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: AP0132-50, AP0132-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P24394\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: The armadillo (ARM) repeat family of proteins are related to the Drosophilamelanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cellmigration, cell proliferation, tissue maintenance and tumorigenesis. They areintracellular proteins and function in signal transduction and cell structure.\u003cbr\u003e\nARMCX3 (armadillo repeat containing, X-linked 3), also known as ALEX3(ARM protein lost in epithelial cancers on chromosome X 3), is a single passmembrane protein belonging to the armadillo repeat family of proteins.ARMCX3 contains three ARM repeats and shares 60% sequence similaritywith the related proteins, ARMCX1 and ARMCX2. ARMCX3 is believed toplay a role in embryonic development and tissue maintenance and may alsofunction as a tumor suppressor.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IL-4R\/CD124(Phospho-Y497) polyclonal antibody detects endogenous levels of IL-4R\/CD124 protein only when phosphorylated at Tyr497.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of IL-4R\/CD124(Phospho-Y497) polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane1:MCF-7 whole cell lysate(40ug)\u003cbr\u003e\nLane2:HCT116 whole cell lysate(40ug)\u003cbr\u003e\nLane3:SGC7901 whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 78 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD_antigen: CD124; Soluble IL-4 receptor subunit alpha; Soluble IL-4R-alpha; sIL4Ralpha\/prot; IL-4-binding protein; IL4-BP; IL4R; 582J2.1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic phosphopeptide derived from human IL-4R\/CD124 around the phosphorylation site of Tyrosine 497.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylation\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42908772794547,"sku":"AP0132-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42908772827315,"sku":"AP0132-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_f315e8cf-7545-4477-93cb-4cf58306427c.jpg?v=1703006895","url":"https:\/\/afsbio.com\/products\/il-4r-cd124phospho-y497-polyclonal-antibody-ap0132","provider":"AFSBio Inc.","version":"1.0","type":"link"}