{"product_id":"il-6-polyclonal-antibody-bs6419","title":"IL-6 Polyclonal Antibody-BS6419","description":"\u003cp\u003eIL-6 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS6419-50, BS6419-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P05231\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIL-6 Polyclonal Antibody-BS6419\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:2000\u003cbr\u003e\nIHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the brea own of fats and to improve insulin resistance.Genetic variations in IL6 are associated with susceptibility to rheumatoid arthritis systemic juvenile. An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IL-6 polyclonal antibody detects endogenous levels of IL-6 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 23 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of IL-6 polyclonal antibody at 1:500 dilution\u003cbr\u003e\n Lane 1: HCC827 whole cell lysate (40ug) \u003cbr\u003e\n Lane 2: PC3 whole cell lysate (40ug, Immunohistochemistry (IHC) analysis of IL-6 pAb in paraffin-embedded Rat Lung tissue.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Interleukin BSF 2; \u003cbr\u003e\nB cell differentiation factor; \u003cbr\u003e\nB cell stimulatory factor 2; \u003cbr\u003e\nB-cell stimulatory factor 2; \u003cbr\u003e\nBSF 2; \u003cbr\u003e\nBSF-2; \u003cbr\u003e\nBSF2; \u003cbr\u003e\nCDF; \u003cbr\u003e\nCTL differentiation factor; \u003cbr\u003e\nCytotoxic T cell differentiation factor; \u003cbr\u003e\nHepatocyte stimulating factor; \u003cbr\u003e\nHGF; \u003cbr\u003e\nHPGF; \u003cbr\u003e\nHSF; \u003cbr\u003e\nHybridoma growth factor; \u003cbr\u003e\nHybridoma growth factor Interferon beta-2; \u003cbr\u003e\nHybridoma plasmacytoma growth factor; \u003cbr\u003e\nIFN-beta-2; \u003cbr\u003e\nIFNB2; \u003cbr\u003e\nIL 6; \u003cbr\u003e\nIL-6; \u003cbr\u003e\nIL6; \u003cbr\u003e\nIL6 protein; \u003cbr\u003e\nIL6; \u003cbr\u003e\nInterferon beta 2; \u003cbr\u003e\nInterferon beta-2; \u003cbr\u003e\nInterleukin 6 (interf\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant full length Human IL-6.\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42962808930483,"sku":"BS6419-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42962808963251,"sku":"BS6419-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_0f8a2f29-3de7-461f-8ec3-43fe2e217be8.jpg?v=1705319055","url":"https:\/\/afsbio.com\/products\/il-6-polyclonal-antibody-bs6419","provider":"AFSBio Inc.","version":"1.0","type":"link"}