{"product_id":"il12b-polyclonal-antibody-bs90699","title":"IL12B Polyclonal Antibody-BS90699","description":"\u003cp\u003eIL12B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90699-50, BS90699-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P29460(Human) P43432(Mouse)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500-1:1,000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK\/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Peptide affinity purified.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of IL12B on differentLysates using anti-IL12B antibody at 1\/500 dilution. \u003cbr\u003e\n Positive control：\u003cbr\u003e\n Lane 1: Hela\u003cbr\u003e\n Lane 2: Mouse placenta\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 37 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IL12B polyclonal antibody detects endogenous levels of IL12B protein.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: IL-12B, CLMF p40, NKSF2, IL12B, NKSF2, CLMF, CLMF p40, CLMF2, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL 12B, IL-12 subunit p40, IL-12B, IL12 p40, IL12B, IL12B, IMD28, IMD29, Interleukin 12 beta chain, Interleukin 12 p40, Interleukin-12 subunit beta, NK cell stimulatory factor chain 2, NKSF, NKSF2,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthetic peptide within mouse IL12B 220-300 aa.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42939200536755,"sku":"BS90699-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42939200569523,"sku":"BS90699-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a1b5e048-7626-45d2-9475-24410cebd954.jpg?v=1704545022","url":"https:\/\/afsbio.com\/products\/il12b-polyclonal-antibody-bs90699","provider":"AFSBio Inc.","version":"1.0","type":"link"}