{"product_id":"il18bp-monoclonal-antibody-mb0143","title":"IL18BP Monoclonal Antibody-MB0143","description":"\u003cp\u003eIL18BP Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB0143-50, MB0143-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O95998\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:400~1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine,IL18. It binds IL18,prevents the binding of IL18 to its receptor,and thus inhibits IL18-induced IFN-gamma production,resulting in reduced T-helper type 1 immune responses.This protein is constitutively expressed and secreted in mononuclear cells.Elevated level of this protein is detected in the intestinal tissues of patients with Crohn´s disease.Alternatively spliced transcript variants encoding different isoforms have been described for this gene.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of IL18BP and does not cross-react with related proteins\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Predicted band size:37KDa\u003cbr\u003e\nObserved band size:37\/40KDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western BlotDetection of IL18BP antibody in CHO-K1 cells transfected by IL18BP-PDGFR fusion protein and K562 cell lysates using IL18BP antibody (1:400-1:1000 diluted).\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: IL18 binding protein; IL-18BP; IL18 BP; IL18 BPa; IL18BP; IL18BPa; Interleukin 18 binding protein; Interleukin-18-binding protein; MC51L 53L 54L homolog gene product; Tadekinig alfa; Tadekinig-alfa.\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant full length Human IL18BP.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42923522031795,"sku":"MB0143-50","price":334.88,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42923522064563,"sku":"MB0143-100","price":576.38,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_74ec0a79-c6ef-45ae-99cf-45b1ae777ad6.jpg?v=1703851090","url":"https:\/\/afsbio.com\/products\/il18bp-monoclonal-antibody-mb0143","provider":"AFSBio Inc.","version":"1.0","type":"link"}