{"product_id":"il1r2-polyclonal-antibody-bs62076","title":"IL1R2 Polyclonal Antibody-BS62076","description":"\u003cp\u003eIL1R2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS62076-50, BS62076-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1 mg\/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P27930\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Non-signaling receptor for IL1A, IL1B and IL1RN. ReducesIL1B activities. Serves as a decoy receptor by competetive bindingto IL1B and preventing its binding to IL1R1. Also modulatescellular response through non-signaling association with IL1RAPafter binding to IL1B. IL1R2 (membrane and secreted forms)preferentially binds IL1B and poorly IL1A and IL1RN. The secretedIL1R2 recruits secreted IL1RAP with high affinity; this complexformation may be the dominant mechanism for neutralization of IL1Bby secreted\/soluble receptors.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IL1R2 polyclonal antibody detects endogenous levels of IL1R2 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of IL1R2 polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane1:Jurkat whole cell lysate(20µg)\u003cbr\u003e\nLane2:HEK293T whole cell lysate(40µg)\u003cbr\u003e\nLane3:The Kidney tissue lysate of Rat(40ug)\u003cbr\u003e\nLane4:The Heart tissue lysate of Mouse(40ug)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 45 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Interleukin-1 receptor type 2; IL-1R-2; IL-1RT-2; IL-1RT2; CD121 antigen-like family member B; CDw121b; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD121b; mIL-1R2; mIL-1RII; \u003cbr\u003e\nsIL-1R2; sIL-1RII; IL1R2; IL1RB\u003c\/p\u003e \n\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human IL1R2\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910470963379,"sku":"BS62076-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910470996147,"sku":"BS62076-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_72857940-b502-4a51-a9fd-84845fcc3cae.jpg?v=1703093055","url":"https:\/\/afsbio.com\/products\/il1r2-polyclonal-antibody-bs62076","provider":"AFSBio Inc.","version":"1.0","type":"link"}