{"product_id":"il3ra-polyclonal-antibody-e-ab-63765","title":"IL3RA Polyclonal Antibody - E-AB-63765","description":"\u003cp\u003eIL3RA Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-63765-60, E-AB-63765-120, E-AB-63765-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IL3RA\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: IL3RA; CD123; IL3R; IL3RAY; IL3RX; IL3RY; hIL-3Ra\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P26951\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2\/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human IL3RA (NP_002174.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IHC \t1:100-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 34kDa\/43kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 70kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146298359987,"sku":"E-AB-63765-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146298392755,"sku":"E-AB-63765-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146298425523,"sku":"E-AB-63765-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b6df5de3-104b-44e1-b69a-a603ebbc43dc.png?v=1710293235","url":"https:\/\/afsbio.com\/products\/il3ra-polyclonal-antibody-e-ab-63765","provider":"AFSBio Inc.","version":"1.0","type":"link"}