{"product_id":"inhibin-beta-a-inhba-polyclonal-antibody-e-ab-92683","title":"Inhibin beta A (INHBA) Polyclonal Antibody - E-AB-92683","description":"\u003cp\u003eInhibin beta A (INHBA) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-92683-60, E-AB-92683-120, E-AB-92683-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Inhibin beta A (INHBA)\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: INHBA; EDF; FRP\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P08476\u003c\/p\u003e\n\n\u003cp\u003eBackground: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth\/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human beta A\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 47kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 47KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146650615987,"sku":"E-AB-92683-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146650648755,"sku":"E-AB-92683-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146650681523,"sku":"E-AB-92683-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e030a968-ac9b-44da-9818-702fdfc6dc20.png?v=1710299359","url":"https:\/\/afsbio.com\/products\/inhibin-beta-a-inhba-polyclonal-antibody-e-ab-92683","provider":"AFSBio Inc.","version":"1.0","type":"link"}