{"product_id":"inpp5j-rabbit-pab-es5542","title":"INPP5J rabbit pAb - ES5542","description":"\u003cp\u003eINPP5J rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES5542-50, ES5542-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: catalytic activity:1D-myo-inositol 1, 3, 4, 5-tetrakisphosphate + H (2)O = 1D-myo-inositol 1, 3, 4-trisphosphate + phosphate., catalytic activity:D-myo-inositol 1, 4, 5-trisphosphate + H (2)O = myo-inositol 1, 4-bisphosphate + phosphate., domain:The 5 Arg-Ser-Xaa-Ser-Xaa-Xaa (RSXSXX) motifs may constitute binding sites for the 14-3-3 protein., function:Inositol 5-phosphatase, which converts inositol 1, 4, 5-trisphosphate to inositol 1, 4-bisphosphate. Also converts phosphatidylinositol 4, 5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1, 3, 4, 5-tetrakisphosphate to inositol 1, 3, 4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles., PTM:Phosphorylated at Ser\/Thr residues., similarity:Belongs to the inositol-1, 4, 5-trisphosphate 5-phosphatase type II family., subcellular location:Predominantly localized to membrane ruffles.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: INPP5J; PIB5PA; PIPP; Phosphatidylinositol 4; 5-bisphosphate 5-phosphatase A; Inositol polyphosphate 5-phosphatase J\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from INPP5J . at AA range: 850-930\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 27124\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q15735\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Predominantly localized to membrane ruffles.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201823301811,"sku":"ES5542-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201823334579,"sku":"ES5542-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_ffdbb1ce-2e5a-4d42-a787-eb7787be852b.png?v=1767112605","url":"https:\/\/afsbio.com\/products\/inpp5j-rabbit-pab-es5542","provider":"AFSBio Inc.","version":"1.0","type":"link"}