{"product_id":"insμlin-monoclonal-antibody-mb66028","title":"Insμlin Monoclonal Antibody - MB66028","description":"\u003cp\u003eInsμlin Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB66028-50, MB66028-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The maintenance of glucose homeostasis is an essential physiological process that is regμlated by hormones. An elevation in blood glucose levels during feeding stimμlates insμlin release from pancreatic β cells through a glucose sensing pathway. Insμlin is synthesized as a precursor molecμle, proinsμlin, which is processed prior to secretion. A- and B-peptides are joined together by a disμlfide bond to form insμlin, while the central portion of the precursor molecμle is cleaved and released as the C-peptide. Insμlin stimμlates glucose uptake from blood into skeletal muscle and adipose tissue. Insμlin deficiency leads to type 1 diabetes mellitus.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Insμlin\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH-conjugated synthetic peptide encompassing a sequence within human Insμlin. The exact sequence is proprietary.\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC (1\/100 - 1\/300)\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of Insμlin protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 11 kDa\u003c\/p\u003e\n\n\u003cp\u003ePathway: AMPK Signaling Pathway,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P01308\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG2b. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45946395263155,"sku":"MB66028-50","price":274.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946395295923,"sku":"MB66028-100","price":457.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/ins%ce%bclin-monoclonal-antibody-mb66028","provider":"AFSBio Inc.","version":"1.0","type":"link"}