{"product_id":"insμlin-receptor-k1368-polyclonal-antibody-bs3744","title":"Insμlin Receptor (K1368) Polyclonal Antibody - BS3744","description":"\u003cp\u003eInsμlin Receptor (K1368) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3744-50, BS3744-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The insμlin receptor (IR) is a heterodimeric protein complex that has an intracellμlar β subunit and an extracellμlar α subunit, which is disμlfide- linked to a transmembrane segment. The insμlin ligand binds to the IR and initiates molecμlar signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insμlin binding to IR induces phosphorylation of intracellμlar tyrosine kinase domains and recruitment of mμltiple SH2 and SH3 domain-containing intracellμlar proteins that serve as signaling intermediates for pleiotropic effects of insμlin.\u003c\/p\u003e \n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Insμlin receptor, IR, CD220, INSR\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 1341-1390 of Human Leu-1.\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Insμlin Receptor (K1368) polyclonal antibody detects endogenous levels of Insμlin Receptor protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 95, 156 kDa\u003c\/p\u003e\n\n\u003cp\u003ePathway: Insμlin \u0026amp;Glucose Signaling,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P06213\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45946261045427,"sku":"BS3744-50","price":274.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946261078195,"sku":"BS3744-100","price":457.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/ins%ce%bclin-receptor-k1368-polyclonal-antibody-bs3744","provider":"AFSBio Inc.","version":"1.0","type":"link"}