{"product_id":"insi2-polyclonal-antibody-bt-ap10395","title":"INSI2 Polyclonal Antibody - BT-AP10395","description":"\u003cp\u003eINSI2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10395-20, BT-AP10395-50, BT-AP10395-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Cell biology;; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: INSIG2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Insulin-induced gene 2 protein\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9Y5U4; Mouse: Q91WG1; Rat: Q80UA9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Insulin-induced gene 2 protein;INSIG-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 51141\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239182852275,"sku":"BT-AP10395-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239182885043,"sku":"BT-AP10395-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239182917811,"sku":"BT-AP10395-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4c4117bd-2db5-4fad-84b2-1c71bfdb6f92.png?v=1769390234","url":"https:\/\/afsbio.com\/products\/insi2-polyclonal-antibody-bt-ap10395","provider":"AFSBio Inc.","version":"1.0","type":"link"}