{"product_id":"integrin-α6-monoclonal-antibody-ra11527","title":"Integrin α6 Monoclonal Antibody - RA11527","description":"\u003cp\u003eIntegrin α6 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA11527-50, RA11527-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: integrin subunit alpha 6 (ITGA6) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2\/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IF\/ICC\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat; Bovine; Dog; Pig\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 3655\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P23229\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45118979408051,"sku":"RA11527-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45118979440819,"sku":"RA11527-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9b9ff23e-f150-4060-aff3-3f421317aab0.png?v=1773343867","url":"https:\/\/afsbio.com\/products\/integrin-%ce%b16-monoclonal-antibody-ra11527","provider":"AFSBio Inc.","version":"1.0","type":"link"}