{"product_id":"integrin-β2-rabbit-pab-es5952","title":"Integrin β2 rabbit pAb - ES5952","description":"\u003cp\u003eIntegrin β2 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES5952-50, ES5952-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: ITGB2; CD18; MFI7; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1\/CR3\/p150; 95 subunit beta; Complement receptor C3 subunit beta; CD antigen CD18\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human CD18\/ITGB2. AA range:720-769\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3689\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P05107\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Single-pass type I membrane protein. Membrane raft; Single-pass type I membrane protein.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201829200051,"sku":"ES5952-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201829232819,"sku":"ES5952-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_d59385f7-945d-4344-ac8f-5636aafbb544.png?v=1767112749","url":"https:\/\/afsbio.com\/products\/integrin-%ce%b22-rabbit-pab-es5952","provider":"AFSBio Inc.","version":"1.0","type":"link"}