{"product_id":"integrin-alpha-5-itga5-cd49e-polyclonal-antibody-e-ab-92445","title":"Integrin alpha 5 (ITGA5\/CD49e) Polyclonal Antibody - E-AB-92445","description":"\u003cp\u003eIntegrin alpha 5 (ITGA5\/CD49e) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-92445-60, E-AB-92445-120, E-AB-92445-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Integrin alpha 5 (ITGA5\/CD49e)\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CD49e; FNRA; VLA-5; VLA5A; Integrin alpha 5; ITGA5\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P08648\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human Integrin alpha 5\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 114kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 150KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146634789043,"sku":"E-AB-92445-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146634821811,"sku":"E-AB-92445-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146634854579,"sku":"E-AB-92445-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_02370d05-8383-4f21-8005-905a06783de1.png?v=1710298974","url":"https:\/\/afsbio.com\/products\/integrin-alpha-5-itga5-cd49e-polyclonal-antibody-e-ab-92445","provider":"AFSBio Inc.","version":"1.0","type":"link"}