{"product_id":"integrin-alpha-5-polyclonal-antibody-bz16736","title":"Integrin alpha 5 Polyclonal Antibody-BZ16736","description":"\u003cp\u003eIntegrin alpha 5 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16736-50, BZ16736-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P08648\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIntegrin alpha 5 Polyclonal Antibody-BZ16736\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ICC\/IF, IP, , FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000 IHC: 1\/50-1\/100 IF: 1\/50-1\/200 IP: 1\/20 FC: 1\/50-1\/100\u003c\/p\u003e\n\n\u003cp\u003eBackground: Integrin alpha-5\/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 115 kDa; Observed MW: 150 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Integrin alpha 5 in mouse heartLysates using Integrin alpha 5 antibody., Immunofluorescence analysis of Integrin alpha 5 in MCF-7 using Integrin alpha 5 antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ITGA5; FNRA; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD49e\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human Integrin alpha 5\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42957329957043,"sku":"BZ16736-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42957329989811,"sku":"BZ16736-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_bd469763-71b5-4b08-8613-1235e45b177e.jpg?v=1705144932","url":"https:\/\/afsbio.com\/products\/integrin-alpha-5-polyclonal-antibody-bz16736","provider":"AFSBio Inc.","version":"1.0","type":"link"}