{"product_id":"integrin-beta-4-polyclonal-antibody-bz17003","title":"Integrin beta 4 Polyclonal Antibody-BZ17003","description":"\u003cp\u003eIntegrin beta 4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ17003-50, BZ17003-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: A2A863\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000 IHC: 1\/50-1\/100\u003c\/p\u003e \n\n\u003cp\u003eBackground: Integrin alpha-6\/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 202 kDa; Observed MW: 202 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Integrin beta 4 in SW480 lysates using Integrin beta 4 antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CD104\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of mouse Integrin beta 4\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42916162470067,"sku":"BZ17003-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42916162502835,"sku":"BZ17003-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_1d9e2e6b-f64a-4375-95bd-e0b06d02ecfc.jpg?v=1703418181","url":"https:\/\/afsbio.com\/products\/integrin-beta-4-polyclonal-antibody-bz17003","provider":"AFSBio Inc.","version":"1.0","type":"link"}