{"product_id":"ip3r-i-phospho-ser1764-rabbit-pab-es5963","title":"IP3R-I (phospho Ser1764) rabbit pAb - ES5963","description":"\u003cp\u003eIP3R-I (phospho Ser1764) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES5963-50, ES5963-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes an intracellular receptor for inositol 1, 4, 5-trisphosphate. Upon stimulation by inositol 1, 4, 5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: ITPR1; INSP3R1; Inositol 1; 4, 5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; InsP3R1; Type 1 inositol 1, 4, 5-trisphosphate receptor; Type 1 InsP3 receptor\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000, Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human IP3R1 around the phosphorylation site of Ser1764. AA range:1730-1779\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3708\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q14643\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Endoplasmic reticulum and secretory granules (By similarity).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201829396659,"sku":"ES5963-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201829429427,"sku":"ES5963-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_103a5093-6641-42cf-aec7-94c71311922a.png?v=1767112756","url":"https:\/\/afsbio.com\/products\/ip3r-i-phospho-ser1764-rabbit-pab-es5963","provider":"AFSBio Inc.","version":"1.0","type":"link"}