{"product_id":"iqgap1-rabbit-pab-es2639","title":"IQGAP1 rabbit pAb - ES2639","description":"\u003cp\u003eIQGAP1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES2639-50, ES2639-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: IQ motif containing GTPase activating protein 1 (IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human IQGAP1. AA range:247-296\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 190kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 8826\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P46940\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane. Nucleus. Cytoplasm. Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1\/S phase (PubMed:20883816).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202089345203,"sku":"ES2639-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202089377971,"sku":"ES2639-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_2cc490e0-3b12-4696-ac4d-703b5b8ee006.png?v=1767121624","url":"https:\/\/afsbio.com\/products\/iqgap1-rabbit-pab-es2639","provider":"AFSBio Inc.","version":"1.0","type":"link"}