{"product_id":"irak-4-monoclonal-antibody-bt-mca0786","title":"IRAK-4 Monoclonal Antibody - BT-MCA0786","description":"\u003cp\u003eIRAK-4 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0786-50, BT-MCA0786-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Immunology; Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: IRAK4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, FCM, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Mouse,Monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Interleukin-1 receptor-associated kinase 4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8TDF7\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 51135\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238360866995,"sku":"BT-MCA0786-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238360899763,"sku":"BT-MCA0786-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c4f8baf0-5076-4c9b-baac-a32c4e059ea2.png?v=1769379165","url":"https:\/\/afsbio.com\/products\/irak-4-monoclonal-antibody-bt-mca0786","provider":"AFSBio Inc.","version":"1.0","type":"link"}