{"product_id":"irf1-polyclonal-antibody-bz16627","title":"IRF1 Polyclonal Antibody-BZ16627","description":"\u003cp\u003eIRF1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16627-50, BZ16627-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P10914\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ICC\/IF, IP, , FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  IF: 1\/50-1\/200  IP: 1\/20  FC: 1\/50-1\/100\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. Defects in IRF1 are a cause of gastric cancer (GASC) [MIM:613659]; also called gastric cancer intestinal or stomach cancer. Gastric cancer is a malignant disease which starts in the stomach, can spread to the esophagus or the small intestine, and can extend through the stomach wall to nearby lymph nodes and organs. It also can metastasize to other parts of the body.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 37 kDa; Observed MW: 48 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of IRF1 in Jurkat lysates using IRF1 antibody., Immunohistochemistry analysis of paraffin-embedded rat kidney using IRF1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunofluorescence analysis of IRF1 in Hela using IRF1 antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: IRF1; Interferon regulatory factor 1; IRF-1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human IRF1\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42993840488627,"sku":"BZ16627-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42993840521395,"sku":"BZ16627-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_e1e3f92b-ab0d-459b-a598-7d9cd0803c83.jpg?v=1706184146","url":"https:\/\/afsbio.com\/products\/irf1-polyclonal-antibody-bz16627","provider":"AFSBio Inc.","version":"1.0","type":"link"}