{"product_id":"irf3-monoclonal-antibody-bt-mca4335","title":"IRF3 Monoclonal Antibody - BT-MCA4335","description":"\u003cp\u003eIRF3 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4335-50, BT-MCA4335-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine\/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: IRF3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5G3E2\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: IRF3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human IRF3 (AA: 1-150) expressed in HEK293-6e cells supernatant.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 47.2kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q14653\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: IIAE7\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3661\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238504718515,"sku":"BT-MCA4335-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238504751283,"sku":"BT-MCA4335-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_419262a8-ba42-4c7a-a98c-a6f036b90f16.png?v=1769381926","url":"https:\/\/afsbio.com\/products\/irf3-monoclonal-antibody-bt-mca4335","provider":"AFSBio Inc.","version":"1.0","type":"link"}