{"product_id":"irk6-polyclonal-antibody-bt-ap10501","title":"IRK6 Polyclonal Antibody - BT-AP10501","description":"\u003cp\u003eIRK6 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10501-20, BT-AP10501-50, BT-AP10501-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KCNJ6\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: G protein-activated inward rectifier potassium channel 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P48051; Mouse: P48542; Rat: P48550\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: G protein-activated inward rectifier potassium channel 2;GIRK-2;BIR1;Inward rectifier K;+ channel Kir3.2;KATP-2;Potassium channel, inwardly rectifying subfamily J member 6\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3763\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239185113267,"sku":"BT-AP10501-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239185146035,"sku":"BT-AP10501-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239185178803,"sku":"BT-AP10501-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2defdff5-dbf3-4704-8519-318f6c4cf99a.png?v=1769390271","url":"https:\/\/afsbio.com\/products\/irk6-polyclonal-antibody-bt-ap10501","provider":"AFSBio Inc.","version":"1.0","type":"link"}