{"product_id":"iscalimab-elisa-kit-db782018","title":"Iscalimab ELISA Kit - DB782018","description":"\u003cp\u003eIscalimab ELISA Kit\u003c\/p\u003e\n\n\u003cp\u003eSize: 96T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: DB782018-96\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eStability and Storage: The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.\u003c\/p\u003e\n\n\u003cp\u003eDetection Method: Colorimetric\u003c\/p\u003e\n\n\u003cp\u003eSample Type: Plasma, Serum\u003c\/p\u003e\n\n\u003cp\u003eAssay Type: Quantitative\u003c\/p\u003e\n\n\u003cp\u003eSensitivity: 0.156 μg\/ml\u003c\/p\u003e\n\n\u003cp\u003eRange: 0.31-5 μg\/mL\u003c\/p\u003e\n\n\u003cp\u003eRecovery: 80-120%\u003c\/p\u003e\n\n\u003cp\u003eBackground: Iscalimab is a new, fully human, monoclonal antibody preventing cluster of differentiation 40 (CD40) pathway signaling and activation of CD40+ cell types. In a recent multicenter, randomized control trial (NCT02217410), with the primary endpoint of non-inferiority on the composite endpoint, iscalimab therapy showed non-inferiority on a composite clinical endpoint, improved renal function, reduced risk for new onset diabetes and similar safety compared with tacrolimus. The analysis presented at the ATC included patients from this study that underwent either routine biopsies or biopsies as part of a follow-up protocol. The data was reviewed and scored by a blinded pathologist using the established Banff criteria and CADI. A CADI of 1 or less was considered as 'normal renal histology'. The average CADI at final biopsy was 1.6 ±0.6 for iscalimab and 5.1 ±0.8 for tacrolimus.\u003c\/p\u003e\n\n\u003cp\u003eShipping: 2-8 ℃\u003c\/p\u003e\n\n\u003cp\u003eFor Research Use Only.\u003c\/p\u003e","brand":"abinScience","offers":[{"title":"Default Title","offer_id":45353678536883,"sku":"DB782018-96","price":1576.4,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/abinscience.png?v=1773676488","url":"https:\/\/afsbio.com\/products\/iscalimab-elisa-kit-db782018","provider":"AFSBio Inc.","version":"1.0","type":"link"}