{"product_id":"isl1-monoclonal-antibody-bt-mca2604","title":"ISL1 Monoclonal Antibody - BT-MCA2604","description":"\u003cp\u003eISL1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2604-50, BT-MCA2604-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ISL1 (ISL1 transcription factor, LIM\/homeodomain) is a member of the LIM\/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Stem cells, Cardiovascular, Neuroscience, Developmental biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ISL1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, ICC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1H9\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ISL1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human ISL1 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 39kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P61371\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Isl-1, ISLET1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3670\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238637953203,"sku":"BT-MCA2604-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238637985971,"sku":"BT-MCA2604-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4cb5e330-8b4f-4845-b23e-36180e8cee98.png?v=1769383302","url":"https:\/\/afsbio.com\/products\/isl1-monoclonal-antibody-bt-mca2604","provider":"AFSBio Inc.","version":"1.0","type":"link"}