{"product_id":"islet-1-monoclonal-antibody-bt-mca0789","title":"Islet-1 Monoclonal Antibody - BT-MCA0789","description":"\u003cp\u003eIslet-1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0789-50, BT-MCA0789-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the LIM\/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Stem cells; Cardiovascular; Neuroscience; Developmental biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ISL1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ICC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Insulin gene enhancer protein ISL-1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P61371; Mouse: P61372\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ISL1; Insulin gene enhancer protein ISL-1; Islet-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3670\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238719807667,"sku":"BT-MCA0789-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238719840435,"sku":"BT-MCA0789-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9d62ee4d-9094-4659-8d8a-f256c9167003.png?v=1769384087","url":"https:\/\/afsbio.com\/products\/islet-1-monoclonal-antibody-bt-mca0789","provider":"AFSBio Inc.","version":"1.0","type":"link"}