{"product_id":"itga3-heavy-chain-cleaved-phe33-rabbit-pab-es20005","title":"ITGA3 (heavy chain, Cleaved-Phe33) rabbit pAb - ES20005","description":"\u003cp\u003eITGA3 (heavy chain, Cleaved-Phe33) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES20005-50, ES20005-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: integrin subunit alpha 3 (ITGA3) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Integrin alpha-3 (CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3; VLA-3 subunit alpha; CD antigen CD49c) [Cleaved into: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain]\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IF; ELISA; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IF\/ICC 1:50-200; ELISA 1:2000-20000; IHC-p 1:50-200\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human ITGA3 (heavy chain, Cleaved-Phe33)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 93 115kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3675\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P26006\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. Cell projection, invadopodium membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein. Enriched preferentially at invadopodia, cell membrane protrusions that correspond to sites of cell invasion, in a collagen-dependent manner.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202425249971,"sku":"ES20005-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202425282739,"sku":"ES20005-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_7989ddcd-fee4-472e-b4d0-04e70def96b6.png?v=1767128920","url":"https:\/\/afsbio.com\/products\/itga3-heavy-chain-cleaved-phe33-rabbit-pab-es20005","provider":"AFSBio Inc.","version":"1.0","type":"link"}