{"product_id":"itgae-light-chain-cleaved-arg177-rabbit-pab-es20010","title":"ITGAE (light chain, Cleaved-Arg177) rabbit pAb - ES20010","description":"\u003cp\u003eITGAE (light chain, Cleaved-Arg177) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES20010-50, ES20010-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: integrin subunit alpha E (ITGAE) Homo sapiens Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Integrin alpha-E (HML-1 antigen; Integrin alpha-IEL; Mucosal lymphocyte 1 antigen; CD antigen CD103) [Cleaved into: Integrin alpha-E light chain; Integrin alpha-E heavy chain]\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human ITGAE (light chain, Cleaved-Arg177)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 17 128kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3682\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P38570\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Membrane; Single-pass type I membrane protein.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202425512115,"sku":"ES20010-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202425544883,"sku":"ES20010-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_31db1a39-c2b8-4e2f-8aa4-deda7b618e5e.png?v=1767128929","url":"https:\/\/afsbio.com\/products\/itgae-light-chain-cleaved-arg177-rabbit-pab-es20010","provider":"AFSBio Inc.","version":"1.0","type":"link"}