{"product_id":"itgae-polyclonal-antibody-e-ab-11334","title":"ITGAE Polyclonal Antibody - E-AB-11334","description":"\u003cp\u003eITGAE Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-11334-60, E-AB-11334-120, E-AB-11334-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ITGAE\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: A530055J10; alpha-E1; alpha-M290; aM290; Antigen CD103; CD 103; CD103; CD103 antigen; HML 1 antigen; HML-1 antigen; HML1 antigen; Human mucosal lymphocyte antigen 1; Human mucosal lymphocyte antigen 1; alpha subunit; Huminae; Integrin alpha E heavy chain; Integrin alpha E light chain; Integrin alpha E; epithelial-associated; Integrin alpha E1; Integrin alpha IEL; Integrin alpha M290; Integrin alpha-E heavy chain; Integrin alpha-IEL; Integrin; alpha E (antigen CD103; human mucosal lymphocyte antigen 1; alpha polypeptide); Integrin; alpha E; ITAE; Itgae; MGC141996; MGC183601; Mucosal lymphocyte 1 antigen; Mucosal lymphocyte antigen 1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology, Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P38570\u003c\/p\u003e\n\n\u003cp\u003eBackground: Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.4 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human ITGAE\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:200-1:1000, IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 130kDa\u003c\/p\u003e\n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136168591539,"sku":"E-AB-11334-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136168624307,"sku":"E-AB-11334-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136168657075,"sku":"E-AB-11334-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2016085c-c5a5-4eab-9aa2-c1fc78a17577.png?v=1709988138","url":"https:\/\/afsbio.com\/products\/itgae-polyclonal-antibody-e-ab-11334","provider":"AFSBio Inc.","version":"1.0","type":"link"}