{"product_id":"itgam-monoclonal-antibody-bt-mca4731","title":"ITGAM Monoclonal Antibody - BT-MCA4731","description":"\u003cp\u003eITGAM Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4731-50, BT-MCA4731-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction, Stem cells, Neuroscience, Tags and cell markers, Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ITGAM\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3A4B10\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ITGAM\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human ITGAM (AA: 623-728) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 127.1kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P11215\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3684\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238384033971,"sku":"BT-MCA4731-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238384066739,"sku":"BT-MCA4731-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_932de306-1e05-4865-95f6-71ba097665a4.png?v=1769379645","url":"https:\/\/afsbio.com\/products\/itgam-monoclonal-antibody-bt-mca4731","provider":"AFSBio Inc.","version":"1.0","type":"link"}