{"product_id":"itgav-light-chain-cleaved-asp891-rabbit-polyclonal-antibody-ra26511","title":"ITGAV (light chain, Cleaved-Asp891) Rabbit Polyclonal Antibody - RA26511","description":"\u003cp\u003eITGAV (light chain, Cleaved-Asp891) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA26511-50, RA26511-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: integrin subunit alpha V (ITGAV) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: Integrin alpha-V (Vitronectin receptor subunit alpha;CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 3685\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 17 110\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P06756\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121363738803,"sku":"RA26511-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121363771571,"sku":"RA26511-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3d30f63a-b087-4c68-bbf8-bbd03d1fdce0.png?v=1773346837","url":"https:\/\/afsbio.com\/products\/itgav-light-chain-cleaved-asp891-rabbit-polyclonal-antibody-ra26511","provider":"AFSBio Inc.","version":"1.0","type":"link"}