{"product_id":"itgb3bp-polyclonal-antibody-e-ab-10402","title":"ITGB3BP Polyclonal Antibody - E-AB-10402","description":"\u003cp\u003eITGB3BP Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-10402-60, E-AB-10402-120, E-AB-10402-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ITGB3BP\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Beta 3 endonexin; Beta3 endonexin; Beta3 endonexin long form; CENP R; CENPR; CENPR; Centromere protein R; endonexin; Beta-3; HSU37139; Integrin beta 3 binding protein (beta3-endonexin); Integrin beta 3 binding protein; NRIF 3; NRIF3; Nuclear receptor interacting factor 3; TAP 20; TAP20\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q13352\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.7 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human ITGB3BP\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136015728819,"sku":"E-AB-10402-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136015761587,"sku":"E-AB-10402-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136015794355,"sku":"E-AB-10402-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_75542104-2134-412e-86d8-1b84eecd5809.png?v=1709987303","url":"https:\/\/afsbio.com\/products\/itgb3bp-polyclonal-antibody-e-ab-10402","provider":"AFSBio Inc.","version":"1.0","type":"link"}