{"product_id":"itpkc-polyclonal-antibody-e-ab-18123","title":"ITPKC Polyclonal Antibody - E-AB-18123","description":"\u003cp\u003eITPKC Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-18123-60, E-AB-18123-120, E-AB-18123-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ITPKC\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 4; 5-trisphosphate 3-kinase C; Inositol 1; inositol 1; 4; 5 trisphosphate 3 kinase C; Inositol trisphosphate 3 kinase C; Inositol-trisphosphate 3-kinase C; InsP 3 kinase C; InsP 3-kinase C; IP3 3-kinase C; IP3 3KC; IP3K C; IP3KC; IP3KC; Itpkc\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q96DU7\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the inositol 1, 4, 5-trisphosphate [Ins(1, 4, 5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1, 4, 5-trisphosphate to 1, 3, 4, 5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.ITPKC (Inositol-Trisphosphate 3-Kinase C) is a Protein Coding gene. Diseases associated with ITPKC include Kawasaki Disease and Lymph Node Disease. Among its related pathways are Inositol phosphate metabolism (KEGG) and Calcium signaling pathway. GO annotations related to this gene include calmodulin binding and inositol-1, 4, 5-trisphosphate 3-kinase activity. An important paralog of this gene is ITPKB.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.08 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human ITPKC\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:30-1:150, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130675003571,"sku":"E-AB-18123-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130675036339,"sku":"E-AB-18123-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130675069107,"sku":"E-AB-18123-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_7d11f50c-54c8-4ce7-b1a6-7875963f0209.png?v=1709811216","url":"https:\/\/afsbio.com\/products\/itpkc-polyclonal-antibody-e-ab-18123","provider":"AFSBio Inc.","version":"1.0","type":"link"}