{"product_id":"jak1-rabbit-pab-es2655","title":"JAK1 rabbit pAb - ES2655","description":"\u003cp\u003eJAK1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES2655-50, ES2655-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha\/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: JAK1; JAK1A; JAK1B; Tyrosine-protein kinase JAK1; Janus kinase 1; JAK-1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF; WB; IP; IHC; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: IF: 1:50-200 Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human JAK1. AA range:988-1037\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 132kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3716\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P23458\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202090164403,"sku":"ES2655-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202090197171,"sku":"ES2655-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_c5612f69-914e-4a44-a634-463b4b9e3610.png?v=1767121638","url":"https:\/\/afsbio.com\/products\/jak1-rabbit-pab-es2655","provider":"AFSBio Inc.","version":"1.0","type":"link"}