{"product_id":"jak3-monoclonal-antibody-bt-mca0798","title":"JAK3 Monoclonal Antibody - BT-MCA0798","description":"\u003cp\u003eJAK3 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0798-50, BT-MCA0798-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Cancer; Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: JAK3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ICC, FCM, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Tyrosine-protein kinase JAK3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P52333; Mouse: Q62137\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3718; Mouse: 16453\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238720266419,"sku":"BT-MCA0798-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238720299187,"sku":"BT-MCA0798-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e82ac481-5b67-454f-9076-d0d0433b7571.png?v=1769384093","url":"https:\/\/afsbio.com\/products\/jak3-monoclonal-antibody-bt-mca0798","provider":"AFSBio Inc.","version":"1.0","type":"link"}