{"product_id":"jak3-phospho-tyr980-981-rabbit-pab-es15392","title":"Jak3 (phospho-Tyr980\/981) rabbit pAb - ES15392","description":"\u003cp\u003eJak3 (phospho-Tyr980\/981) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES15392-50, ES15392-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized phosho peptide around human Jak3 (Tyr980 and 981)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 125kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3718\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P52333\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Endomembrane system; Peripheral membrane protein. Cytoplasm.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202414469299,"sku":"ES15392-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202414502067,"sku":"ES15392-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_8186dec2-b171-4944-aded-0b3fdab236ee.png?v=1767128656","url":"https:\/\/afsbio.com\/products\/jak3-phospho-tyr980-981-rabbit-pab-es15392","provider":"AFSBio Inc.","version":"1.0","type":"link"}