{"product_id":"jak3-phospho-tyr980-981-rabbit-polyclonal-antibody-bt-ap10727","title":"Jak3 (Phospho-Tyr980\/981) Rabbit Polyclonal Antibody - BT-AP10727","description":"\u003cp\u003eJak3 (Phospho-Tyr980\/981) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10727-20, BT-AP10727-50, BT-AP10727-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Epigenetics and nuclear signaling; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: JAK3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Jak3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P52333; Mouse: Q62137; Rat: Q63272\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Jak3;Tyr980\/981; Tyrosine-protein kinase JAK3; EC 2.7.10.2; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3718; Mouse: 16453\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239001186483,"sku":"BT-AP10727-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239001219251,"sku":"BT-AP10727-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239001252019,"sku":"BT-AP10727-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_dbbb33b9-2104-4e30-990c-0f660010857c.png?v=1769387790","url":"https:\/\/afsbio.com\/products\/jak3-phospho-tyr980-981-rabbit-polyclonal-antibody-bt-ap10727","provider":"AFSBio Inc.","version":"1.0","type":"link"}