{"product_id":"jaml1-polyclonal-antibody-bt-ap10569","title":"JAML1 Polyclonal Antibody - BT-AP10569","description":"\u003cp\u003eJAML1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10569-20, BT-AP10569-50, BT-AP10569-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The Ig-like V-type domain 2 mediates interaction with CXADR.,May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.,induction:Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells.,Belongs to the immunoglobulin superfamily.,Contains 2 Ig-like V-type (immunoglobulin-like) domains.,subcellular location:Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN.,subunit:Interacts with CXADR.,tissue specificity:Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus.,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: AMICA1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Junctional adhesion molecule-like\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q86YT9; Mouse: Q80UL9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Junctional adhesion molecule-like;Adhesion molecule interacting with CXADR antigen 1;Dendritic cell-specific protein CREA7-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 120425\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239187177651,"sku":"BT-AP10569-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239187210419,"sku":"BT-AP10569-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239187243187,"sku":"BT-AP10569-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c01130b1-3eab-44ec-a46d-5b480de4b6a6.png?v=1769390301","url":"https:\/\/afsbio.com\/products\/jaml1-polyclonal-antibody-bt-ap10569","provider":"AFSBio Inc.","version":"1.0","type":"link"}