{"product_id":"jaml1-rabbit-pab-es10721","title":"JAML1 rabbit pAb - ES10721","description":"\u003cp\u003eJAML1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES10721-50, ES10721-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: domain:The Ig-like V-type domain 2 mediates interaction with CXADR., function:May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells., induction:Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells., similarity:Belongs to the immunoglobulin superfamily., similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains., subcellular location:Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN., subunit:Interacts with CXADR., tissue specificity:Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus.,\u003c\/p\u003e \n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthesized peptide derived from part region of human protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 43kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 120425\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q86YT9\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Single-pass type I membrane protein. Cell junction. Localized at the plasma membrane and enriched in areas of cell-cell contacts (PubMed:12869515).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201736007859,"sku":"ES10721-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201736040627,"sku":"ES10721-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_a6ac1d15-f402-4bd6-b5c5-bfc3ffa0a68a.png?v=1767110618","url":"https:\/\/afsbio.com\/products\/jaml1-rabbit-pab-es10721","provider":"AFSBio Inc.","version":"1.0","type":"link"}