{"product_id":"jnk3-monoclonal-antibody-bt-mca0802","title":"JNK3 Monoclonal Antibody - BT-MCA0802","description":"\u003cp\u003eJNK3 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0802-50, BT-MCA0802-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Cancer; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MAPK10\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ICC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Mitogen-activated protein kinase 10\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P53779; Mouse: Q61831\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MAPK10; JNK3; JNK3A; PRKM10; SAPK1B; Mitogen-activated protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated protein kinase 1b; SAPK1b; Stress-activated protein kinase JNK3; c-Jun N-terminal kinase 3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5602\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238721085619,"sku":"BT-MCA0802-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238721118387,"sku":"BT-MCA0802-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6c4ce0ae-1152-4ad2-ac28-3da1eca8b7d8.png?v=1769384100","url":"https:\/\/afsbio.com\/products\/jnk3-monoclonal-antibody-bt-mca0802","provider":"AFSBio Inc.","version":"1.0","type":"link"}