{"product_id":"jt-v1-polyclonal-antibody-ap6009","title":"Jt V1 Polyclonal Antibody-AP6009","description":"\u003cp\u003eJt V1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers:AP6009-50, AP6009-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q13155\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Jt V1, also known as P38 or AIMP2 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 2), is a 320 amino acid nuclear and cytoplasmic protein that is a component of the aminoacyl-tRNA synthase complex. Containing one GST C-terminal domain, Jt V1 mediates ubiquitination and degradation of FBP1, a transcriptional activator of c-Myc, leading to c-Myc down-regulation, which is required for aveolar type II cell differentiation. Jt V1 also participates in blocking MDM2-mediated ubiquitination, degradation of p53 and functions as a proapoptotic factor.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 35 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Jt V1 polyclonal antibody detects endogenous levels of Jt V1 protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003cbr\u003e\nAlternative Name: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Multisynthase complex auxiliary component p38; Protein Jt V-1; AIMP2; Jt V1; PRO0992\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant full length Human Jt V1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42895059746995,"sku":"AP6009-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42895059779763,"sku":"AP6009-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_9ac7e2f8-992e-46e0-b25d-0902497e388f.jpg?v=1702573149","url":"https:\/\/afsbio.com\/products\/jt-v1-polyclonal-antibody-ap6009","provider":"AFSBio Inc.","version":"1.0","type":"link"}