{"product_id":"jtv1-polyclonal-antibody-ap6009","title":"JTV1 Polyclonal Antibody - AP6009","description":"\u003cp\u003eJTV1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: AP6009-50, AP6009-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: JTV1, also known as P38 or AIMP2 (aminoacyl tRNA synthetase complex-interacting mμltifunctional protein 2), is a 320 amino acid nuclear and cytoplasmic protein that is a component of the aminoacyl-tRNA synthase complex. Containing one GST C-terminal domain, JTV1 mediates ubiquitination and degradation of FBP1, a transcriptional activator of c-Myc, leading to c-Myc down-regμlation, which is required for aveolar type II cell differentiation. JTV1 also participates in blocking MDM2-mediated ubiquitination, degradation of p53 and functions as a proapoptotic factor.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Aminoacyl tRNA synthase complex-interacting mμltifunctional protein 2, Mμltisynthase complex auxiliary component p38, Protein JTV-1, AIMP2, JTV1, PRO0992\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fμll length Human JTV1.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: JTV1 polyclonal antibody detects endogenous levels of JTV1 protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 35 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q13155\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45936725622963,"sku":"AP6009-50","price":274.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45936725655731,"sku":"AP6009-100","price":457.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image.jpg?v=1788296056","url":"https:\/\/afsbio.com\/products\/jtv1-polyclonal-antibody-ap6009","provider":"AFSBio Inc.","version":"1.0","type":"link"}