{"product_id":"junctional-adhesion-molecule-1-monoclonal-antibody-mb12089","title":"Junctional Adhesion Molecule 1 Monoclonal Antibody-MB12089","description":"\u003cp\u003eJunctional Adhesion Molecule 1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB12089-50, MB12089-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9Y624\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\/IF, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IF: 1\/50-1\/200  IP: 1\/20\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 33 kDa; Observed MW: 33 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Junctional Adhesion Molecule 1\/JAMA in Hela, A549 lysates using Junctional Adhesion Molecule 1 antibody., Immunocytochemistry analysis of Junctional Adhesion Molecule 1\/JAMA in MCF-7 using Junctional Adhesion Molecule 1\/JAMA antibody, and DAPI\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human Junctional Adhesion Molecule 1\/JAM-A\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42975403704499,"sku":"MB12089-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42975403737267,"sku":"MB12089-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_81111497-baaa-480a-9c16-528963fed045.jpg?v=1705665513","url":"https:\/\/afsbio.com\/products\/junctional-adhesion-molecule-1-monoclonal-antibody-mb12089","provider":"AFSBio Inc.","version":"1.0","type":"link"}