{"product_id":"k1c40-rabbit-polyclonal-antibody-es15364","title":"K1C40 Rabbit Polyclonal Antibody - ES15364","description":"\u003cp\u003eK1C40 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES15364-50, ES15364-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human K1C40 AA range: 143-193\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: K1C40\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of K1C40 at Human\/Mouse\/Rat\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000, IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Expressed in skin and scalp, Also very weakly expressed in tongue, breast, colon and small intestine, In the hair follicle, it is specifically present in the upper hair cuticle, Not present in the upper cortex (at protein level),\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 47kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Estrogen signaling pathway, Staphylococcus aureus infection\u003c\/p\u003e\n\n\u003cp\u003eFunction: Developmental Stage: During differentiation of the hair, it is one of the last keratins expressed\u003cbr\u003e\nFunction: May play a role in late hair differentiation\u003cbr\u003e\nMiscellaneous: There are two types of cytoskeletal and microfibrillar keratin, I (acidic) and II (neutral to basic) (40-55 and 56-70 kDa, respectively)\u003cbr\u003e\nSimilarity: Belongs to the intermediate filament family\u003cbr\u003e\nSubunit: Heterotetramer of two type I and two type II keratins\u003cbr\u003e\nTissue Specificity: Expressed in skin and scalp. Also very weakly expressed in tongue, breast, colon and small intestine. In the hair follicle, it is specifically present in the upper hair cuticle. Not present in the upper cortex (at protein level)\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: intermediate filament,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: KRT40 KA36\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: K1C40\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 406221\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q6IFX3\u003c\/p\u003e\n\n\u003cp\u003eRat Gene ID: 287679\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: Q6IFW2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315273879731,"sku":"ES15364-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315273912499,"sku":"ES15364-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/k1c40-rabbit-polyclonal-antibody-es15364","provider":"AFSBio Inc.","version":"1.0","type":"link"}