{"product_id":"kat2b-pcaf-polyclonal-antibody-bs74236","title":"KAT2B\/PCAF Polyclonal Antibody-BS74236","description":"\u003cp\u003eKAT2B\/PCAF Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS74236-50, BS74236-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q92831\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eKAT2B\/PCAF Polyclonal Antibody-BS74236\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\/ICC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB,1:500 - 1:2000  |  IF\/ICC,1:50 - 1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and\/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300\/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300\/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 93kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of extracts of various cell lines, using KAT2B\/PCAF antibody at 1:1000 dilution.\u003cbr\u003e\nSecondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.\u003cbr\u003e\nLysates\/proteins: 25ug per lane.\u003cbr\u003e\nBlocking buffer: 3% non-fat dry milk in TBST.\u003cbr\u003e\nDetection: ECL Basic Kit.\u003cbr\u003e\nExposure time: 90s., Immunofluorescence analysis of U2OS cells using KAT2B\/PCAF Rabbit pAb at dilution of 1:100. Blue: DAPI for nuclear staining.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: KAT2B; CAF; P\/CAF; PCAF\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human KAT2B\/PCAF(NP_003875.3).\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42957336379571,"sku":"BS74236-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42957336412339,"sku":"BS74236-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_627606c0-c5d8-461c-95da-d477908a21f2.jpg?v=1705145028","url":"https:\/\/afsbio.com\/products\/kat2b-pcaf-polyclonal-antibody-bs74236","provider":"AFSBio Inc.","version":"1.0","type":"link"}