{"product_id":"kat6b-monoclonal-antibody-bt-mca2375","title":"KAT6B Monoclonal Antibody - BT-MCA2375","description":"\u003cp\u003eKAT6B Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2375-50, BT-MCA2375-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a histone acetyltransferase and component of the MOZ\/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KAT6B\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 8C8D12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: KAT6B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human KAT6B (AA: 1186-1318) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 231.4kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q8WYB5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: qkf, MORF, MOZ2, GTPTS, MYST4, ZC2HC6B, querkopf\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 23522\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238421029043,"sku":"BT-MCA2375-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238421061811,"sku":"BT-MCA2375-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_caf11f4d-f300-4afc-b52d-c1f31ec64b9e.png?v=1769380483","url":"https:\/\/afsbio.com\/products\/kat6b-monoclonal-antibody-bt-mca2375","provider":"AFSBio Inc.","version":"1.0","type":"link"}