{"product_id":"kat6b-rabbit-pab-a17116","title":"KAT6B Rabbit pAb - A17116","description":"\u003cp\u003eKAT6B Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A17116-20, A17116-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a histone acetyltransferase and component of the MOZ\/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 231kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 280kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 23522\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q8WYB5\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: qkf; MORF; MOZ2; GTPTS; MYST4; ZC2HC6B; querkopf; KAT6B\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Epigenetic writers and erasers of core Histones.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: KAT6B\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189701828787,"sku":"A17116-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189701861555,"sku":"A17116-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_ecda98be-95d1-428b-b800-f807ad2b6285.png?v=1766432998","url":"https:\/\/afsbio.com\/products\/kat6b-rabbit-pab-a17116","provider":"AFSBio Inc.","version":"1.0","type":"link"}