{"product_id":"kcna1-polyclonal-antibody-e-ab-67529","title":"KCNA1 Polyclonal Antibody - E-AB-67529","description":"\u003cp\u003eKCNA1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-67529-60, E-AB-67529-120, E-AB-67529-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: KCNA1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: KCNA1; AEMK; EA1; HBK1; HUK1; KV1.1; MBK1; MK1; RBK1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q09470\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human KCNA1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 56kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 56kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146446733491,"sku":"E-AB-67529-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146446766259,"sku":"E-AB-67529-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146446799027,"sku":"E-AB-67529-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_73b0f04a-d7f3-47af-baae-f1b4116845f4.png?v=1710295722","url":"https:\/\/afsbio.com\/products\/kcna1-polyclonal-antibody-e-ab-67529","provider":"AFSBio Inc.","version":"1.0","type":"link"}